Tissue transglutaminase antibody (tTG), IgA class — the primary test ordered to screen for celiac disease. It is the most sensitive and specific blood test for celiac disease and is the single test preferred by the American College of Gastroenterology, according to its 213 guidelines, as well as the American Gastroenterology Association for the detection of celiac disease in those over the age of 2 years. The IgG class of anti-tTG may be ordered as an alternative in those who have a deficiency of IgA. If the anti-tTG, IgA or IgG test is positive, then the test can also be used to monitor a person with celiac disease and to help evaluate the effectiveness of treatment; antibody levels should fall when gluten is removed from the diet. Although "tissue" is in the name of these tests, they are measured in the blood.Quantitative immunoglobulin A (IgA) test — ordered along with, prior to, or following an anti-tTG test to detect IgA deficiency, which occurs about 2-3% of the time in people with celiac disease and can lead to false-negative test results. If a person has an IgA deficiency, then a test to detect the IgG class of autoantibodies may be ordered.Deamidated gliadin peptide (DGP) antibodies (anti-DGP), IgA or IgG — may be positive in some people with celiac disease who are negative for anti-tTG, especially children less than 2 years old. It may sometimes be ordered with or following an anti-tTG test, especially if anti-tTG is negative. DGP IgG testing along with anti-tTG IgG is recommended by the American College of Gastroenterology for people who have low IgA or IgA deficiency. If the anti-DGP test is positive, it may be used to monitor celiac disease.
Sample Type - Blood
Reporting Time - 72 Hrs
Prerequisites - No special preparation required
Price - ₹2010/-
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