Cancer Antigen 125 (CA-125) is a tumor marker primarily used to monitor therapy during treatment for ovarian cancer. CA-125 is also used to detect whether cancer has come back after treatment is complete. A series of CA-125 tests that shows rising or falling concentrations is often more useful than a single result.CA-125 is sometimes used along with transvaginal ultrasound to test and monitor women who have a high risk for ovarian cancer but who do not yet have the disease. The most significant risk factor for ovarian cancer is an inherited genetic mutation in one of two genes: breast cancer gene1 (BRCA1) or breast cancer gene 2 (BRCA2). Other risk factors are family history, increasing age, reproductive history and infertility, use of hormone replacement therapy, and obesity.Sometimes a CA-125 test may be ordered along with a transvaginal ultrasound to help investigate a lump in woman's lower abdominal area (pelvic mass.)The test is not used, however, to screen women for ovarian cancer because it is non-specific. The U.S. Preventive Services Task Force recommends against screening women for ovarian cancer. This recommendation applies to asymptomatic women but not to women at high risk for developing ovarian cancer, such as those with a genetic mutation.Currently, there is no one reliable method for early detection of ovarian cancer among asymptomatic women. Less than 2% of ovarian cancers are found in the early stages before they have spread outside the ovary. One reason they go undetected is that the symptoms of ovarian cancer are fairly non-specific. In the meantime, regular physicals, pelvic exams, and an awareness of family history and other risk factors are important. (For more about ovarian cancer, see the "What is being tested/" section or the article on Ovarian Cancer.)
Sample Type - Blood
Reporting Time - 1 Day
Prerequisites - No special preparation required
Price - ₹840/-
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